Calcium induced alterations in structural and functional role of phospholipids in Microsporum gypseum.
Indian J Biochem Biophys
;
1995 Jun; 32(3): 166-9
Article
in English
| IMSEAR
| ID: sea-27486
ABSTRACT
The effect of calcium on the structural and functional aspects of phospholipids in Microsporum gypseum was examined. Cells grown in presence of calcium exhibited increased content of phospholipids and enhanced synthesis of phospholipids as monitored by the incorporation of [32P] orthophosphoric acid. The rise in the levels of phospholipids was found to be due to increased synthesis of fatty acids as observed from [14C] acetate incorporation studies. The rise in the levels of phospholipids were reflected in the subcellular fractions also. Change in the phospholipid composition increased the fluidity of the membrane as is evident from fluorescence polarization studies using 1-anilinonaphthalene-8-sulfonate (ANS) and 1,6-diphenyl-1,3,5-hexatriene (DPH). The increased membrane fluidity was consistent with the enhanced uptake of [3H] proline in calcium grown cells.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phospholipids
/
Structure-Activity Relationship
/
Subcellular Fractions
/
Calcium
/
Microsporum
Language:
English
Journal:
Indian J Biochem Biophys
Year:
1995
Type:
Article
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