Effect of picroliv on low density lipoprotein receptor binding of rat hepatocytes in hepatic damage induced by paracetamol.
Indian J Biochem Biophys
;
1992 Oct; 29(5): 428-32
Article
in English
| IMSEAR
| ID: sea-27676
ABSTRACT
Picroliv from root and rhizome of Picrorhiza kurroa showed reversal of low density lipoprotein (LDL) binding to paracetamol-induced damaged hepatocytes of rats. Changes in levels of glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase, conjugated dienes and lipids of hepatocytes were significantly prevented by picroliv at different doses. The effect of picroliv on enzyme levels, LDL receptor binding and lipids in damaged hepatocytes was found to be comparable to silymarin, a known hepatoprotective agent.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aspartate Aminotransferases
/
Rats
/
Rats, Inbred Strains
/
Vanillic Acid
/
Humans
/
Male
/
Receptors, LDL
/
Plant Extracts
/
Cell Survival
/
Cells, Cultured
Language:
English
Journal:
Indian J Biochem Biophys
Year:
1992
Type:
Article
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