Cellular AATF gene: armour against HIV-1.
Indian J Biochem Biophys
;
2007 Oct; 44(5): 276-8
Article
in English
| IMSEAR
| ID: sea-27966
ABSTRACT
Outcome of HIV-1 infection at the cellular level is decided by the orchestrated balance that exists between cellular nucleic acid-based adaptive immune mechanism involving non-coding micro RNAs (miRNAs) and offensive tactics of HIV-1 to suppress this host cellular immunity. In this context, the review explains the importance of a novel miRNA encoded exclusively and conspicuously by HIV-1 genome that has the ability to specifically target cellular AATF gene recognized to play a crucial role in the maintenance of adaptive immunity at nucleic acid level against HIV-1 invasion.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Repressor Proteins
/
Transcription Factors
/
Humans
/
Cell Physiological Phenomena
/
HIV-1
/
Apoptosis
/
MicroRNAs
/
Apoptosis Regulatory Proteins
Language:
English
Journal:
Indian J Biochem Biophys
Year:
2007
Type:
Article
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