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Multiple isoforms of protein kinase C in lymphocytes and airway smooth muscle of guinea pig.
Indian J Biochem Biophys ; 2001 Aug; 38(4): 280-4
Article in English | IMSEAR | ID: sea-28493
ABSTRACT
The isoenzyme pattern of protein kinase C (PKC) in lymphocytes and airway smooth muscles (ASM) was examined by Western blot using commercially available monoclonal antibodies. The results showed the presence of PKC alpha, beta, gamma, epsilon, eta, mu and zeta in lymphocytes and PKC alpha, gamma, epsilon, eta and zeta in ASM. The unexpected feature was the presence of PKCgamma in both lymphocytes and ASM of guinea pigs. Expression of this PKC isoform is usually restricted to tissues in the central nervous system or spinal cord. Expression of PKC delta, theta, lambda and tau was not detected in either lymphocytes or ASM.
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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Protein Kinase C / Male / Lymphocytes / Blotting, Western / Guinea Pigs / Isoenzymes / Animals / Antibodies, Monoclonal / Muscle, Smooth Language: English Journal: Indian J Biochem Biophys Year: 2001 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Protein Kinase C / Male / Lymphocytes / Blotting, Western / Guinea Pigs / Isoenzymes / Animals / Antibodies, Monoclonal / Muscle, Smooth Language: English Journal: Indian J Biochem Biophys Year: 2001 Type: Article