Membrane guanylate cyclase signal transduction system.
Indian J Biochem Biophys
;
1997 Feb-Apr; 34(1-2): 40-9
Article
in English
| IMSEAR
| ID: sea-28581
ABSTRACT
The suspect role of the receptor-mediated cyclic GMP signaling pathway was dispelled by the discovery of a membrane guanylate cyclase that was also an atrial natriuretic factor receptor. It is now established that the membrane guanylate cyclase transduction system is linked to the signaling of natriuretic factors, guanylin/enterotoxin, and emerging evidence suggests that a new neural tissue-specific subfamily of membrane guanylate cyclases exists whose mechanism of signal transduction is different from those of the other membrane cyclases. This review will briefly discuss the fascinating, albeit turbulent, history of this signal transduction field, which will be followed by its current status and finally the direction it is heading.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Binding Sites
/
Humans
/
Signal Transduction
/
Cell Membrane
/
Adenosine Triphosphate
/
Receptors, Atrial Natriuretic Factor
/
Cyclic GMP
/
History, 20th Century
/
Guanylate Cyclase
/
Animals
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Biochem Biophys
Year:
1997
Type:
Article
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