Response of lung transfer components to grades of smoking.
Indian J Chest Dis Allied Sci
;
1990 Jan-Mar; 32(1): 33-8
Article
in English
| IMSEAR
| ID: sea-29251
ABSTRACT
Pulmonary functions were studied in 50 healthy, asymptomatic, 20 to 47 years, male smokers along with 50 healthy non-smokers matched for age, height, socio-economic status and physical activity. Smokers consumed 2-30 cigarettes per day with duration of smoking ranging from 2 to 26 years. In smokers FEF, V75. PEF and MVV were significantly reduced whereas FRC was increased significantly. Pulmonary diffusion function as assessed by TLCO showed significant reduction. While Vc showed progressive decrease with increasing duration and quantity of smoking, DM increased in the beginning but gradually declined later. TLCO showed a better negative correlation with quantity than with duration of smoking even when the effect of other factors was excluded. Decrease in TLCO is probably due to bronchoconstriction and reflex vasospasm of pulmonary vasculature. Co-efficient of diffusion KCO was also decreased in smokers.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Smoking
/
Pulmonary Gas Exchange
/
Vital Capacity
/
Adult
/
Lung
/
Middle Aged
Language:
English
Journal:
Indian J Chest Dis Allied Sci
Year:
1990
Type:
Article
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