Drug resistant Haemophilus influenzae from respiratory tract infection in a tertiary care hospital in north India.
Indian J Chest Dis Allied Sci
;
2001 Jan-Mar; 43(1): 13-7
Article
in English
| IMSEAR
| ID: sea-30111
ABSTRACT
Haemophilus influenzae is an important respiratory pathogen. Emergence of resistance to various antibiotics is a major problem in patient management. A total of 90 strains of H. influenzae were characterized from specimens obtained from patients of acute respiratory tract infection; 13 (14.4%) belonged to type beta. On biotyping, 90% strains belonged to biotype II. The frequency of resistance to various antibiotics was as follows cotrimoxazole 33.3% ampicillin 21.1%, cephalexin 7.8%, chloramphenicol 7.8%, ciprofloxacin 2.5% erythromycin and tetracycline 5% each. All the ampicillin-resistant strains produced beta-lactamase as detected by nitrocefin disc method. None of the strains exhibited resistance to cefaclor and third generation cephalosporins. The present study showed emergence of variable resistance to ampicillin, cotrimoxazole and other antibiotics. It is important for the clinical microbiology laboratory to monitor drug resistant strains for instituting appropriate antibiotic therapy of respiratory infections due to H. influenzae.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Respiratory Tract Infections
/
Female
/
Humans
/
Male
/
Drug Resistance, Microbial
/
Child
/
Child, Preschool
/
Haemophilus influenzae
/
Adolescent
/
Pneumonia, Bacterial
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Chest Dis Allied Sci
Year:
2001
Type:
Article
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