Thymic histology in myasthenia gravis.
Indian J Chest Dis Allied Sci
;
1992 Jul-Sep; 34(3): 117-21
Article
in English
| IMSEAR
| ID: sea-30245
ABSTRACT
Histological features of resected thymuses of 18 patients with myasthenia gravis were evaluated. Thymoma were seen in 16.6% of the patients. In the non-thymomatous group, thymic hyperplasia with follicle formation was seen in 33.3%, involuted thymus with occasional lymphoid follicle formation in 11.1%, thymitis with B cell infiltration in 16.6%, involuted thymus in 11.1% and normal thymus in 11.1% of patients. Immuno-histological staining for B and T lymphocytes delineated the group labelled as thymitis with B cell infiltration. Mast cell and eosinophils were frequently seen in thymuses with thymic hyperplasia with follicle formation and thymitis with B cell infiltration. Thymic hyperplasia with follicle formation was more frequent in young patients and these patients had better prognosis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thymus Gland
/
Female
/
Humans
/
Male
/
Child
/
Adult
/
Middle Aged
/
Myasthenia Gravis
Language:
English
Journal:
Indian J Chest Dis Allied Sci
Year:
1992
Type:
Article
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