Adrenocortical insufficiency in smear positive pulmonary tuberculosis.
Indian J Chest Dis Allied Sci
;
1992 Jul-Sep; 34(3): 133-6
Article
in English
| IMSEAR
| ID: sea-30475
ABSTRACT
We studied 40 patients with pulmonary tuberculosis. All were positive for acid-fast bacilli (AFB) in the sputum. Their mean age was 30 yrs (range 10-50 yrs) and the duration of illness was 26.3 +/- 2.3 months. Radiologically minimal, moderately advanced and far advanced lesions were present in 7 (17.5%), 9 (22.5%) and 23 (57.5%) patients respectively. One patient with endobronchial lesion had no radiological evidence of pulmonary tuberculosis. Clinically, 14 patients (35%) had one or the other features of adrenocortical insufficiency. Postural hypotension was the commonest feature and was present in 11 patients (27.5%), followed by nausea and vomiting (20%), loss of axillary hair and libido (10%), skin and mucosal pigmentation in 7.5% of the cases. ACTH stimulation revealed incomplete adrenocortical insufficiency (partially responsive adrenal) in 5 patients (12.5%) and complete adrenocortical insufficiency (non-responsive adrenal) in 2 patients (5%). Patients with features of adrenal insufficiency had significantly longer duration of illness (p < 0.001) but there was no correlation with extent or type of lesion.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Tuberculosis, Pulmonary
/
Female
/
Humans
/
Male
/
Child
/
Adolescent
/
Adrenal Cortex
/
Adrenal Cortex Function Tests
/
Adrenal Insufficiency
/
Adult
Language:
English
Journal:
Indian J Chest Dis Allied Sci
Year:
1992
Type:
Article
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