Repeated doses of albendazole against strongyloidiasis in Thai children.
Southeast Asian J Trop Med Public Health
;
1989 Jun; 20(2): 221-6
Article
in English
| IMSEAR
| ID: sea-30790
ABSTRACT
Fifty children aged 5 to 12 years whose fecal examination confirmed of strongyloidiasis were divided into 2 groups. One group (Group I) of 26 received 400 mg albendazole once a day for 3 consecutive days. The other group (Group II) of 24 received the same dosage but repeated a week later. Simple smear fecal examination was performed for 3 consecutive days before treatment, and stool cultures were performed on Days 13, 14, 15 21, 22 and 23 after treatment. Evaluation of successful treatment or cure was based on the absence of larvae in 6 culture specimens. The cure rates were 80.8% in Group I and 91.7% in Group II (p = 0.18). Side effect consisted of mild and transient vomiting in one patient in each group. Although the difference in cure rates between the two drug regimens was not statistically different, two courses of treatment (Group II) resulted in a higher cure rate.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Strongyloidiasis
/
Thailand
/
Female
/
Humans
/
Male
/
Drug Administration Schedule
/
Albendazole
/
Child
/
Child, Preschool
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1989
Type:
Article
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