Cis-platinum-adriamycin-cyclophosphamide in the treatment of advanced-recurrent cervical cancer.
Southeast Asian J Trop Med Public Health
;
1985 Dec; 16(4): 660-4
Article
in English
| IMSEAR
| ID: sea-31231
ABSTRACT
Twenty-two patients with advanced or recurrent cancer of the cervix treated with cis-platinum, adriamycin and cyclophosphamide were evaluated. Nine of 22 (41% achieved objective response (2 CR + 7PR), 9/22 (41%) stable disease, 4/22 (18%) progressive disease. The mean duration of response was 24.6 weeks, with a range of 18-28 weeks. Patients with poorly differentiated histologic grade and without previous treatment had better response rates. Responders had longer survival (mean 63.5 + weeks) than nonresponders (mean 30.5 weeks). Commonly encountered toxicities were alopecia, nausea and vomiting, and leucopenia, which were all tolerable.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aged
/
Female
/
Humans
/
Carcinoma, Squamous Cell
/
Antineoplastic Combined Chemotherapy Protocols
/
Doxorubicin
/
Uterine Cervical Neoplasms
/
Cisplatin
/
Adult
/
Cyclophosphamide
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1985
Type:
Article
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