The effect of praziquantel treatment on liver and spleen size of children with schistosomiasis in Napu Valley, central Sulawesi.
Southeast Asian J Trop Med Public Health
;
1990 Mar; 21(1): 91-4
Article
in English
| IMSEAR
| ID: sea-31665
ABSTRACT
Forty-six school children with japonicum schistosomiasis living in a village at Napu Valley, Indonesia were treated with praziquantel at a dosage of 70 mg/kg in two divided doses in a day. The number of children with palpable liver dropped significantly from 95.6% before treatment to 58.7% after treatment. The size of the liver was reduced in the majority of cases with a virtual disappearance of cases with very large liver (10 cm). Post-treatment increase of the liver size was observed in all 8 cases with small pre-treatment livers (0.5-1 cm). In contrast to the changes of the size of the liver after treatment, the number of children with palpable spleens before and after treatment was not significantly altered.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Praziquantel
/
Splenomegaly
/
Schistosomiasis japonica
/
Female
/
Humans
/
Male
/
Child
/
Child, Preschool
/
Adolescent
/
Hepatomegaly
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1990
Type:
Article
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