Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients.
Southeast Asian J Trop Med Public Health
;
2007 Sep; 38(5): 881-5
Article
in English
| IMSEAR
| ID: sea-32172
ABSTRACT
In order to investigate and compare the presence of Helicobacter pylori VacA in primary liver cancer specimens (12 hepatocellular carcinoma and 6 cholangiocarcinoma) and control liver specimens (7 non-primary liver cancer) from Thai patients who underwent liver resection, H. pylori VacA gene was assayed in extracted DNA by real-time polymerase chain reaction. The selected amplicons revealed high homology compared with H. pylori VacA sequence. H. pylori VacA gene was detected in all primary liver cancer specimens and in 71% (5/7) of control liver specimens.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Bacterial Proteins
/
Aged
/
Female
/
Humans
/
Male
/
Molecular Sequence Data
/
Base Sequence
/
Polymerase Chain Reaction
/
Helicobacter pylori
Type of study:
Diagnostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
2007
Type:
Article
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