Evaluation of a new fourth-generation microwell enzyme-linked immunosorbent assay for detection of HIV-1 subtype B and E antibodies.
Southeast Asian J Trop Med Public Health
;
2001 Mar; 32(1): 177-9
Article
in English
| IMSEAR
| ID: sea-32180
ABSTRACT
The recent fourth-generation enzyme-immunoassays have been used to increase the sensitivity for detecting HIV-1 antibodies and reduce the window period of HIV infection. The HIV antigens utilized in those assays were prepared from HIV-1 clade B which is different from HIV-1 subtypes circulating in Thailand. We evaluated 323 HIV-1 seropositives either B or E subtype to determine whether they were detected with the new combined anti-HIV and the p24 Ag assay. Under evaluation we found that this enzyme immunoassay manufactured by Organon Teknika showed the high sensitivity and specificity with a greater delta (delta) value with B than E subtypes samples (+15.29 vs +5.73).
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Peptide Fragments
/
Species Specificity
/
Humans
/
Enzyme-Linked Immunosorbent Assay
/
Molecular Sequence Data
/
HIV Antibodies
/
HIV Envelope Protein gp120
/
Sensitivity and Specificity
/
Amino Acid Sequence
/
HIV-1
Type of study:
Diagnostic study
/
Evaluation studies
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS