Studies on paragonimiasis: treatment with mebendazole, emetine with mebendazole and praziquantel.
Southeast Asian J Trop Med Public Health
;
1984 Sep; 15(3): 354-9
Article
in English
| IMSEAR
| ID: sea-32369
ABSTRACT
One hundred cases of paragonimiasis from Saraburi province, Thailand were studied with respect to epidemiology, clinical manifestations, radiography and treatment. Highly endemic areas were Cha-om and Sum-pugpaew villages in Kang-koy district. The ratio of male to female was 4852. Uncooked crabs and shrimps are the second intermediate hosts of Paragonimus. Hemoptysis and chronic cough were the main symptoms; with crepitations and rhonchi in both lungs. There was no specific changes in chest X-rays of the lungs, except in cases of hemoptysis where changes in pulmonary vessels were observed. Tomograms of the lungs provided 100% accuracy and confirmation of diagnosis of pulmonary paragonimiasis. Praziquantel 25 my/kg body weight three times a day for 2 days gave a cure rate of 90%, mebendazole plus emetine hydrochloride gave a cure rate of 70% and mebendazole alone was not effective.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Paragonimiasis
/
Parasite Egg Count
/
Praziquantel
/
Thailand
/
Benzimidazoles
/
Female
/
Humans
/
Male
/
Child
/
Clinical Trials as Topic
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1984
Type:
Article
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