Larvicidal, adulticidal and repellent effects of Kaempferia galanga.
Southeast Asian J Trop Med Public Health
;
1999 Sep; 30(3): 470-6
Article
in English
| IMSEAR
| ID: sea-32380
ABSTRACT
Four fractions of Kaempferia galanga (hexane fraction, dichloromethane fraction 1, dichloromethane fraction 2 and methanolic fraction) were tested for larvicidal activity toward fourth instar Culex quinquefasciatus. The hexane fraction was found to exhibit the highest larvicidal effect with the LC50 of 42.33 ppm. Testing for adulticidal activity, the hexane fraction did not show any promising adulticidal effect. However, it caused a knockdown effect which might be useful as a repellent. It was then tested for repellent activity in human volunteers both in laboratory and field studies. In a laboratory study, the hexane fraction possessed repellency against Aedes aegypti (ED50 value of 30.73 microg/cm2), and provided biting protection for 3 hours. In a field study, it could protect against certain mosquitos, ie, Armigeres subalbatus, Anopheles barbirostris, An. aconitus, Mansonia uniformis, Cx. quinquefasciatus, Cx. gelidus, Cx. tritaeniorhynchus and Ae. aegypti. The hexane fraction did not cause dermal irritation when applied on human skin.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Male
/
Drugs, Chinese Herbal
/
Plant Extracts
/
Mosquito Control
/
Regression Analysis
/
Aedes
/
Culex
/
Insect Repellents
/
Insecticides
Type of study:
Diagnostic study
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1999
Type:
Article
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