Hydrophobicity and antifilarial activities of 4-aminoquinolines.
Southeast Asian J Trop Med Public Health
;
1982 Dec; 13(4): 658-61
Article
in English
| IMSEAR
| ID: sea-32613
ABSTRACT
The apparent partition coefficients (Papp.) of eight 4-aminoquinolines in 1-octanol/pH 7.4 buffered solutions have been determined and correlated with their reported antifilarial activities. Antifilarial activity appears to be present only in those 4-aminoquinolines which have log Papp. values falling within a narrow range of 2.8 to 3.2.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Solubility
/
Chemistry
/
Chemistry, Physical
/
Chemical Phenomena
/
Filaricides
/
Aminoquinolines
/
Anthelmintics
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1982
Type:
Article
Similar
MEDLINE
...
LILACS
LIS