Antioxidant enzyme levels in the erythrocytes of riboflavin-deficient and Trichinella spiralis-infected rats.
Southeast Asian J Trop Med Public Health
;
2003 Sep; 34(3): 480-5
Article
in English
| IMSEAR
| ID: sea-32736
ABSTRACT
The erythrocyte antioxidant enzyme levels of catalase, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) of riboflavin-deficient and Trichinella spiralis-infected rats were investigated. The rats were deprived of riboflavin at the 8th week of the experiment. At that time, the erythrocyte glutathione reductase activity coefficient (EGR AC), as an indicator of riboflavin status, was > or = 1.30 in rats fed a riboflavin-deficient diet and T. spiralis-infected rats fed a riboflavin-deficient diet showed no biochemical sign of riboflavin deficiency. At the 12th week of the experiment, the levels of catalase, SOD and GSH-Px were significantly lower in the riboflavin-deficient, T. spiralis-infected, and combined riboflavin-deficient and T. spiralis-infected, rats, compared to the control group. This may have been due to an increase in free oxygen radicals caused by riboflavin deficiency and parasitic infection.
Full text:
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Index:
IMSEAR (South-East Asia)
Main subject:
Rats
/
Riboflavin Deficiency
/
Superoxide Dismutase
/
Trichinellosis
/
Catalase
/
Analysis of Variance
/
Trichinella spiralis
/
Rats, Wistar
/
Statistics, Nonparametric
/
Disease Susceptibility
Type of study:
Evaluation studies
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
2003
Type:
Article
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