Antimalarial activity of concanamycin A alone and in combination with pyronaridine.
Southeast Asian J Trop Med Public Health
;
2006 Jul; 37(4): 619-21
Article
in English
| IMSEAR
| ID: sea-33232
ABSTRACT
Concanamycin A, a macrolide antibiotic inhibitor of vacuolar H+-ATPase derived from Streptomyces sp, inhibited Plasmodium falciparum K1 growth in culture with an IC500 value of 0.2 nM. It exhibited an additive effect when tested together with the antimalarial pyronaridine.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Plasmodium falciparum
/
Macrolides
/
Inhibitory Concentration 50
/
Animals
/
Naphthyridines
/
Antimalarials
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
2006
Type:
Article
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