Affinity and response of Burkholderia pseudomallei and Burkholderia cepacia to insulin.
Southeast Asian J Trop Med Public Health
;
1996 Sep; 27(3): 584-91
Article
in English
| IMSEAR
| ID: sea-33321
ABSTRACT
The cells of Burkholderia pseudomallei, B. cepacia and Pseudomonas aeruginosa grown on agar plates were stained with fluorescently-labeled insulin. The former two species were stained positively indicating insulin binding but P. aeruginosa was not. Insulin exposure reduced phospholipase C and acid phosphatase activities of B. pseudomallei but did not affect those enzymatic activities of B. cepacia in the employed experimental conditions. It is suggested that B. pseudomallei have insulin receptors which may be associated with a signal transfer system involving phospholipase and protein tyrosine phosphatase.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Type C Phospholipases
/
Acid Phosphatase
/
Humans
/
Burkholderia pseudomallei
/
Burkholderia cepacia
/
Burkholderia Infections
/
Diabetes Complications
/
Diabetes Mellitus
/
Hydrogen-Ion Concentration
/
Insulin
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1996
Type:
Article
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