Artemether in moderate to severe malaria: a multicenter trial in India.
Southeast Asian J Trop Med Public Health
;
1997 Dec; 28(4): 736-40
Article
in English
| IMSEAR
| ID: sea-33501
ABSTRACT
154 patients suffering from acute attack of moderate to severe malaria caused by Plasmodium falciparum were treated with 480 mg artemether, administered intramuscularly (i.m.) in six equally divided doses at 12 hour intervals. Results showed a rapid parasite clearance. Mean parasite clearance time (PCT) was found to be 23.65 +/- 1.57 hours. Mean fever clearance time (FCT) was 35.28 +/- 1.7 hours. Adverse drug events (ADE) were mild and self-limiting. Recrudescence rate (RR) among the patients followed up was 4.55%. We conclude that artemether is a safe and effective anti-malarial agent for the treatment of moderate and severe cases of P. falciparum malaria.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Recurrence
/
Sesquiterpenes
/
Severity of Illness Index
/
Female
/
Humans
/
Male
/
Single-Blind Method
/
Acute Disease
/
Malaria, Falciparum
/
Adult
Type of study:
Controlled clinical trial
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1997
Type:
Article
Similar
MEDLINE
...
LILACS
LIS