Albendazole treatment for Giardia intestinalis infections in school children.
Southeast Asian J Trop Med Public Health
;
1999 Mar; 30(1): 78-83
Article
in English
| IMSEAR
| ID: sea-33580
ABSTRACT
A randomized controlled trial, 113 school children with Giardia intestinalis infection were treated with albendazole or tinidazole. Albendazole 400 mg once a day x 3 days and tinidazole 50 mg/kg single dose were given orally to 62 and 51 children, respectively. Parasitological cure was documented when there were > or = 2 times negative stool examination for G. intestinalis at 1-2 weeks after therapy. Thirty-one of 62 (50%) children treated with albendazole and 49 of 51 (96.1%) children treated with tinidazole had parasitological cure (p < 0.001). No major side effects were observed except one case in tinidazole group had severe headache for 30 hours. Albendazole appears to be safe and produced a moderate cure rate for G. intestinalis infection when a 3 day anthelmintic regimen is given.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Tinidazole
/
Female
/
Humans
/
Male
/
Child Nutrition Disorders
/
Abdominal Pain
/
Albendazole
/
Child
/
Child, Preschool
Type of study:
Controlled clinical trial
/
Prevalence study
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1999
Type:
Article
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