Studies on human filariasis in Malaysia: immunodiagnosis using indirect immunofluorescence.
Southeast Asian J Trop Med Public Health
;
1979 Dec; 10(4): 486-97
Article
in English
| IMSEAR
| ID: sea-33623
ABSTRACT
The indirect immunofluorescence test using sonicated microfilariae of Brugia malayi has been evaluated on 173 sera from patients and persons exposed to Wuchereria bancrofti and B. malayi in endemic areas of Peninsular Malaysia. In the microfilaria-negative group, without signs and symptoms of filariasis 55/62 sera (89%) had titers of 116 and less. In the microfilaremic groups and in the amicrofilaremic cases with clinical filariasis, all the sera tested were positive, with the antibody titers ranging generally from 116 - 1256. Cross-reaction tests were done on 16 samples of onchocerciasis sera from West Africa using sonicated antigen as well as antigen-coated CNB1-activated sepharose. Antibody titers were detected in all the sera. The usefulness of the sonicated microfilarial antigen in serodiagnosis of filariasis is discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Wuchereria bancrofti
/
Brugia
/
Female
/
Humans
/
Male
/
Child
/
Child, Preschool
/
Fluorescent Antibody Technique
/
Adolescent
/
Adult
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1979
Type:
Article
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