Antimutagenic activity of Sesbania javanica Miq. flower DMSO extract and its major flavonoid glycoside.
Southeast Asian J Trop Med Public Health
;
2005 Nov; 36(6): 1543-51
Article
in English
| IMSEAR
| ID: sea-33929
ABSTRACT
The antimutagenic activity of Sesbania javanica Miq. or Sano, an edible vegetable flower DMSO extract against aflatoxin B1 (AFB1) benzo (a) pyrene [B(a)P], was evaluated by means of the Ames' test. The Sesbania javanica Miq. flower DMSO extract showed a strong inhibitory effect against AFB1 and B(a)P mutagens. A search to isolate the major flavonoid in Sesbania javanica Miq. flower extract found the flavonol glycoside, Quercetin 3-2(G)-rhamnosylrutinoside, which was confirmed by its physicochemical properties as a major constituent of the flower. Quercetin 3-2(G)-rhamnosylrutinoside (207 microg/plate) also showeda strong inhibitory effect against AFB1 and B(a)P with a more than 70% inhibition rate.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Flavonoids
/
Humans
/
Plant Extracts
/
Dimethyl Sulfoxide
/
Antimutagenic Agents
/
Aflatoxin B1
/
Flowers
/
Sesbania
/
Glycosides
/
Mutagenicity Tests
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
2005
Type:
Article
Similar
MEDLINE
...
LILACS
LIS