Dengue virus infection of the central nervous system (CNS): a case report from Brazil.
Southeast Asian J Trop Med Public Health
;
2002 Mar; 33(1): 68-71
Article
in English
| IMSEAR
| ID: sea-34035
ABSTRACT
Dengue infection that is accompanied by unusual complications has been described in Brazil. We report on the presence of dengue virus in the central nervous system (CNS) of a patient who died in 1998 in Rio Grande do Norte, northeast Brazil. DEN-2 viruses were isolated from the brain liver, and lymphnode tissue of a 67-year-old man whose signs and symptoms were those of dengue infection and a secondary immune response. A postmortem revealed nose bleeds a liver that was brownish with yellow areas, and pulmonary and cerebrae congestion. Immunoperoxidase staining showed a dengue antigen-specific positive reaction in the gray matter cells of the cerebrall cortex; a granular citoplasmatic reaction was seen in the neurons. Dengue infection should always be considered as a cause encephalitis in tropical countries, especially in those where the disease is endemic.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Brazil
/
Aged
/
Humans
/
Male
/
Central Nervous System Infections
/
Fatal Outcome
/
Dengue
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
2002
Type:
Article
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