Zinc and copper status of thalassemic children.
Southeast Asian J Trop Med Public Health
;
1997 Dec; 28(4): 877-80
Article
in English
| IMSEAR
| ID: sea-34146
ABSTRACT
We investigated the amount of both zinc and copper in plasma, erythrocytes and hair in 11 patients with hemoglobin H disease, 59 patients with beta-thalassemia/HbE disease and 20 patients with homozygous beta-thalassemia. Plasma and hair zinc levels were found to be much lower, but erythrocyte zinc levels were higher, in thalassemic patients than in controls. The levels of copper in both plasma and erythrocytes were higher in the patients than in the controls. The mechanism with respect to the increase of the amount of both zinc and copper in erythrocytes was not clear; this result may reflect the impairment of zinc and copper utilization in tissues in the pathogenesis of these thalassemic patients.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Zinc
/
Female
/
Humans
/
Male
/
Case-Control Studies
/
Child
/
Child, Preschool
/
Adolescent
/
Beta-Thalassemia
/
Alpha-Thalassemia
Type of study:
Observational study
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1997
Type:
Article
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