Prenatal diagnosis of thalassemia in Songklanagarind Hospital in southern Thailand.
Southeast Asian J Trop Med Public Health
;
1998 Dec; 29(4): 795-800
Article
in English
| IMSEAR
| ID: sea-34154
ABSTRACT
A thalassemia screening program for pregnant women has been established in Songklanagarind Hospital since 1992. After genetic counseling, a total of 5078 pregnant women accepted entry into a screening program for thalassemia. Couples at risk who should receive prenatal diagnosis were 2.8%. Total cases who accepted prenatal diagnosis were 135. Total clinical cases were 40 (29.6%) with achievement by prenatal diagnosis of 33 cases (82.5%). Genetic amniocentesis is the most acceptable method for prenatal diagnosis. Five cases (12.5%) were misdiagnosed due to contamination of maternal blood cells in amniotic fluid cases. Questionable results were reported in 2 cases (5%). Abortion occurred in one case (0.7%). Improvement of surgical technic in prenatal diagnosis reduced the complications and contamination of maternal cells. This program shows the feasibility of prevention and control of thalassemia disease in southern Thailand.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prenatal Diagnosis
/
Thailand
/
Female
/
Humans
/
Male
/
Pregnancy
/
Chorionic Villi Sampling
/
Hydrops Fetalis
/
Carrier State
/
Genetic Testing
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1998
Type:
Article
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