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Detection through screening of maternal thyrotoxicosis induced central hypothyroidism in newborns.
Southeast Asian J Trop Med Public Health ; 2003 ; 34 Suppl 3(): 150-1
Article in English | IMSEAR | ID: sea-34279
ABSTRACT
Use of a third generation TSH assay enabled extremely low values of TSH to be detected through newborn screening. The use of a supplemental free thyroxine improved testing specificity. The hypothyroidism observed is believed to be secondary to suppression of the hypothalamic-pituitary-thyroid axis by placentally transferred maternal thyroxine.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Pregnancy Complications / Thyroxine / Thyrotoxicosis / Female / Humans / Infant, Newborn / Pregnancy / Thyrotropin / Sensitivity and Specificity / Neonatal Screening Type of study: Diagnostic study / Screening study Language: English Journal: Southeast Asian J Trop Med Public Health Year: 2003 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Pregnancy Complications / Thyroxine / Thyrotoxicosis / Female / Humans / Infant, Newborn / Pregnancy / Thyrotropin / Sensitivity and Specificity / Neonatal Screening Type of study: Diagnostic study / Screening study Language: English Journal: Southeast Asian J Trop Med Public Health Year: 2003 Type: Article