Ivermectin and diethylcarbamazine trials in leaf monkeys (Presbytis cristatus) infected with Wuchereria kalimantani.
Southeast Asian J Trop Med Public Health
;
1992 Jun; 23(2): 288-92
Article
in English
| IMSEAR
| ID: sea-34852
ABSTRACT
Clinical trials of Ivermectin in single oral doses of 200, 400, and 1,000 mg/kg body weight or in multiple doses of 200 mg/kg body weight for 5 consecutive days were performed in leaf monkeys (Presbytis cristatus) infected with Wuchereria kalimantani. Optimal microfilaricidal effect occurred at 200 mg/kg body weight. The drug was less effective than diethylcarbamazine in this animal model for human filariasis but had no adverse effects.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Parasitic Diseases
/
Placebos
/
Wuchereria
/
Ivermectin
/
Cercopithecidae
/
Haplorhini
/
Diethylcarbamazine
/
Animals
/
Microfilariae
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1992
Type:
Article
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