vWf levels as a circulating marker of endothelial dysfunction in patients with hypertrophic cardiomyopathy.
Indian Heart J
;
2005 Nov-Dec; 57(6): 655-7
Article
in English
| IMSEAR
| ID: sea-3521
ABSTRACT
BACKGROUND:
The aim of the present study was to investigate whether the von Willebrand factor levels, as a possible indicator of endothelial dysfunction, is increased in hypertrophic cardiomyopathy, and also whether it is related to the clinical status of hypertrophic cardiomyopathy. METHODS ANDRESULTS:
The study group comprised 29 patients with hypertrophic cardiomyopathy and 29 healthy age- and gender-matched control subjects. There was no significant difference in von Willebrand factor levels between study group (77.0 +/- 23.1%) and control group (88.5 +/- 34.2%). There was no statistically significant difference between control group (88.5 +/- 34.2%) and functional class I/II group (82.0 +/- 24.3%), between control group and functional class III group (67.6 +/- 18.3%) and between functional class I/II group and functional class III group with respect to the von Willebrand factor levels.CONCLUSIONS:
The results suggest that von Willebrand factor levels, as a possible indicator of endothelial dysfunction, are not increased in patients with hypertrophic cardiomyopathy and von Willebrand factor levels are not related to functional class in these patients.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Reference Values
/
Severity of Illness Index
/
Aged
/
Female
/
Humans
/
Male
/
Von Willebrand Factor
/
Endothelium, Vascular
/
Cardiomyopathy, Dilated
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
Indian heart j
Year:
2005
Type:
Article
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