Double-dose ivermectin vs albendazole for the treatment of gnathostomiasis.
Southeast Asian J Trop Med Public Health
;
2005 May; 36(3): 650-2
Article
in English
| IMSEAR
| ID: sea-35512
ABSTRACT
A comparative study was performed for the treatment of gnathostomiasis patients with ivermectin 0.2 mg/kg for 2 days in 15 patients vs albendazole 400 mg twice daily for 21 days in 14 patients. The ivermectin and albendazole gave cure rates of 100% and 78.5%, respectively, however the difference was not statistically significant between the two drugs (Fisher's exact, p=0.0996). One year after treatment, the patients who had no migratory swellings and a drop in ELISA titers or a negative immunoblot test were considered to be cured. The side effect of ivermectin for two days was dizziness. The side effects of albendazole were nausea, dizziness, and an increased alkaline phosphatase.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Ivermectin
/
Humans
/
Enzyme-Linked Immunosorbent Assay
/
Albendazole
/
Treatment Outcome
/
Spirurida Infections
/
Eosinophils
/
Gnathostoma
/
Animals
Type of study:
Controlled clinical trial
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
2005
Type:
Article
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