Pulmonary artery obstruction in thalassaemia.
Southeast Asian J Trop Med Public Health
;
1980 Dec; 11(4): 516-23
Article
in English
| IMSEAR
| ID: sea-35615
ABSTRACT
A new feature has been encountered in review of a large species of autopsy materials of beta-thalassaemia/Hb E disease. Among 43 patients pulmonary arterial obstructive lesions were found in 19 (44%), of which 17 were splenectomised cases. The pulmonary arterial thromboembolism may have been due to circulating platelet aggregates. This newly discovered pathology may be an additional factor contributing toward dyspnoea and heart failure in thalassaemia besides anaemia and cardiac iron deposition. If it is proven that this pulmonary arterial thromboembolism is indeed due to circulating platelet aggregates, preventive measure by administration of drugs reducing platelet aggregation such as aspirin and Persantin may be indicated, especially after splenectomy.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pulmonary Artery
/
Splenectomy
/
Thalassemia
/
Thromboembolism
/
Aged
/
Female
/
Humans
/
Male
/
Child
/
Child, Preschool
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1980
Type:
Article
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