A dot-ELISA test using monoclonal antibody-purified antigens for the diagnosis of paragonimiasis caused by Paragonimus heterotremus.
Southeast Asian J Trop Med Public Health
;
1997 Sep; 28(3): 621-3
Article
in English
| IMSEAR
| ID: sea-35875
ABSTRACT
A dot enzyme-linked immunosorbent assay (dot-ELISA) using antigens purified by monoclonal antibody-affinity chromatography was developed for detecting antibodies to Paragonimus heterotremus in four groups of subjects. They consisted of 30 patients with P. heterotremus infection, 93 patients with other parasitic infections, 18 patients with pulmonary tuberculosis and 30 normal, healthy controls. Sensitivity, specificity, as well as positive and negative predictive values of the test were 100, 97, 88, and 100%, respectively.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Paragonimiasis
/
Paragonimus
/
Thailand
/
Humans
/
Enzyme-Linked Immunosorbent Assay
/
Immunoblotting
/
Case-Control Studies
/
Reproducibility of Results
/
Chromatography, Affinity
/
Sensitivity and Specificity
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1997
Type:
Article
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