Evidence of vitamin K deficiency in cord blood.
Southeast Asian J Trop Med Public Health
;
1993 ; 24 Suppl 1(): 116-20
Article
in English
| IMSEAR
| ID: sea-35930
ABSTRACT
The prevalence of vitamin K deficiency in the newborns delivered at Siriraj Hospital was studied. The prolongation of one stage prothrombin time and the presence of PIVKA-II (non carboxylated prothrombin antigen) in cord blood were interpreted as the secondary change from vitamin K deficiency state. The most reliable method to diagnose vitamin K deficiency is the detection of vitamin K level in plasma which is not yet available in Thailand. Although the prevalence of vitamin K deficiency in the newborns from our data is not high, only 0.6%, it is shown that some of the apparently normal newborn infants may have bleeding problem from vitamin K deficiency in both newborn and early infancy periods. So, the correction of this deficiency by administration of vitamin K to all newborns is appropriate and reasonable decision.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Protein Precursors
/
Prothrombin Time
/
Thailand
/
Vitamin K
/
Female
/
Humans
/
Male
/
Blood Coagulation Factors
/
Infant, Newborn
/
Prothrombin
Type of study:
Diagnostic study
/
Prevalence study
/
Prognostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1993
Type:
Article
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