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Evidence of vitamin K deficiency in cord blood.
Southeast Asian J Trop Med Public Health ; 1993 ; 24 Suppl 1(): 116-20
Article in English | IMSEAR | ID: sea-35930
ABSTRACT
The prevalence of vitamin K deficiency in the newborns delivered at Siriraj Hospital was studied. The prolongation of one stage prothrombin time and the presence of PIVKA-II (non carboxylated prothrombin antigen) in cord blood were interpreted as the secondary change from vitamin K deficiency state. The most reliable method to diagnose vitamin K deficiency is the detection of vitamin K level in plasma which is not yet available in Thailand. Although the prevalence of vitamin K deficiency in the newborns from our data is not high, only 0.6%, it is shown that some of the apparently normal newborn infants may have bleeding problem from vitamin K deficiency in both newborn and early infancy periods. So, the correction of this deficiency by administration of vitamin K to all newborns is appropriate and reasonable decision.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Protein Precursors / Prothrombin Time / Thailand / Vitamin K / Female / Humans / Male / Blood Coagulation Factors / Infant, Newborn / Prothrombin Type of study: Diagnostic study / Prevalence study / Prognostic study Country/Region as subject: Asia Language: English Journal: Southeast Asian J Trop Med Public Health Year: 1993 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Protein Precursors / Prothrombin Time / Thailand / Vitamin K / Female / Humans / Male / Blood Coagulation Factors / Infant, Newborn / Prothrombin Type of study: Diagnostic study / Prevalence study / Prognostic study Country/Region as subject: Asia Language: English Journal: Southeast Asian J Trop Med Public Health Year: 1993 Type: Article