Development of the second generation Japanese encephalitis (JE) vaccine.
Southeast Asian J Trop Med Public Health
;
1988 Sep; 19(3): 493-500
Article
in English
| IMSEAR
| ID: sea-36179
ABSTRACT
Recent analysis of Japanese encephalitis (JE) virus genome RNA, especially its nucleotide sequence, revealed the localization of virion envelope glycoprotein (E) gene on the virus genome. Since the E protein is the major protective antigen related with the virus neutralization, attempts have been made to produce the second generation JE vaccine by expressing the E protein using recombinant DNA technologies. These studies will eventually lead to control JE by mass-vaccination in several Asian countries where JE is one of the major public health problems.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
DNA, Circular
/
Enzyme-Linked Immunosorbent Assay
/
Viral Vaccines
/
Cells, Cultured
/
Viral Envelope Proteins
/
Aedes
/
Electrophoresis, Polyacrylamide Gel
/
Encephalitis Virus, Japanese
/
Animals
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
1988
Type:
Article
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