TT virus infection in acute non-A to E hepatitis in northern Thailand.
Southeast Asian J Trop Med Public Health
;
2001 Dec; 32(4): 814-22
Article
in English
| IMSEAR
| ID: sea-36221
ABSTRACT
TT virus is a novel DNA virus widely distributed in the general population. We examined the prevalence of TTV infection in a population with acute non-A to E hepatitis and in comparison groups located in Northern Thailand. The prevalence of TTV in subjects with non-A-E hepatitis was 19% (21/112), 6% (4/72) in healthy volunteers, 17% (12/72) in those with hepatitis A or B, and 17% (8/48) in hospitalized patients with non-hepatitis illnesses. A significant association with TTV infection and non-A-E hepatitis was seen in all groups (OR 3.9, p = 0.02) and in children (OR 25.8, p = 0.001). Among subjects with non-A-E hepatitis, TTV was associated with higher alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels (significant for AST, p = 0.02). Our observations suggest that TTV in our study population may be associated with non-A-E hepatitis and that children in particular may be at risk of hepatocellular injury as a result of TTV infection.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aspartate Aminotransferases
/
Thailand
/
Female
/
Humans
/
Male
/
Base Sequence
/
Child
/
Prevalence
/
Adolescent
/
DNA Primers
Type of study:
Prevalence study
Country/Region as subject:
Asia
Language:
English
Journal:
Southeast Asian J Trop Med Public Health
Year:
2001
Type:
Article
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