Airway provocation test with ragweed pollen extract in Chinese asthmatics.
Asian Pac J Allergy Immunol
;
1994 Dec; 12(2): 125-9
Article
in English
| IMSEAR
| ID: sea-36601
ABSTRACT
As ragweed becomes widespread over China, ragweed pollenosis tends to be more frequent. Incidence of ragweed pollenosis is about 1.04% in Qingdao district. To elucidate ragweed as an allergen in the development of bronchial asthma, ragweed pollen extract inhalation airway provocation tests (APT) were studied in 55 patients with ragweed pollenosis. A single dosage of 9,000 PNU ragweed pollen extract was applied and positive response was defined as more than 35% fall in SGrs at the dose of PT35-Grs. Among 55 patients, positive APTs were found in 27 cases (49%), dual late-phase responses in 11 patients, single late-phase responses in 2 patients in the complicated asthma group. Late-phase responses were related to the increased specific IgE and strong positive skin test response (wheal > 11 mm). The results suggested ragweed pollen was one of the important allergens causing bronchial asthma. There was airway hyperresponsiveness to ragweed pollen in some patients (20%) with ragweed pollenosis without asthmatic symptoms.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pollen
/
Asthma
/
Bronchial Provocation Tests
/
Female
/
Humans
/
Male
/
Immunoglobulin E
/
Skin Tests
/
Allergens
/
Plant Extracts
Country/Region as subject:
Asia
Language:
English
Journal:
Asian Pac J Allergy Immunol
Year:
1994
Type:
Article
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