Immune status in congenital infections by TORCH agents in pregnant Thais.
Asian Pac J Allergy Immunol
;
1997 Jun; 15(2): 93-7
Article
in English
| IMSEAR
| ID: sea-36709
ABSTRACT
A cross-sectional, sero-epidemiological survey of the prevalence of antibodies to TORCH agents during various stages of gestation revealed an overall rate of 13-15 percent having antibodies to Toxoplasma gondii; 85-87 percent, to rubella ; 79-81 percent, to herpes simplex virus (HSV); 100 percent, to cytomegalovirus (CMV); 82-86 percent, to human herpes virus type 6 (HHV-6); 1-2 percent, to hepatitis C virus (HCV). None of human T lymphotropic virus type I (HTLV-I) antibody was detected, and a prevalence of hepatitis B surface antigen (HBsAg) was 6 percent. Although a tendency was noted towards an increase of antibody detection to each TORCH agent as gestation progressed, a statistically significant increase in antibodies titer and specific IgM antibody was found with regard to CMV. These results suggest an increase in CMV infection or reactivation during pregnancy whereas an increase in the other TORCH infections was not obvious.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pregnancy Trimester, Second
/
Pregnancy Trimester, Third
/
Pregnancy Trimester, First
/
Rubella
/
Thailand
/
Female
/
Humans
/
Virus Diseases
/
Immunoglobulin M
/
Pregnancy
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Asian Pac J Allergy Immunol
Year:
1997
Type:
Article
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