Comparison study of combined DTPw-HB vaccines and separate administration of DTPw and HB vaccines in Thai children.
Asian Pac J Allergy Immunol
;
1999 Jun; 17(2): 113-20
Article
in English
| IMSEAR
| ID: sea-36812
ABSTRACT
The safety, immunogenicity and tolerability of two different DTPw-HBV combination vaccines, containing 5 and 10 microg of HBsAg; were investigated in comparison with separate administration of DTPw and HBV (10 microg of HBsAg). A three dose primary vaccination course at 2, 4 and 6 months of age was followed by a booster dose at 18 months. All vaccines were safe and well tolerated. The DTPw-HBV combination vaccine containing 10 microg of HBsAg elicited significantly higher anti-HBs titres than the other two vaccines after the primary and booster vaccination course. All vaccines elicited a high response against the other components. Based on these results, DTPw-HBV (10 microg HBsAg) was the most effective vaccine at this schedule.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pain
/
Sleep Stages
/
Time Factors
/
Humans
/
Diphtheria-Tetanus-Pertussis Vaccine
/
Vaccination
/
Hepatitis B Vaccines
/
Vaccines, Combined
/
Erythema
/
Fever
Type of study:
Controlled clinical trial
Language:
English
Journal:
Asian Pac J Allergy Immunol
Year:
1999
Type:
Article
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