Toxoplasma gondii antibodies in HIV and non-HIV infected Thai pregnant women.
Asian Pac J Allergy Immunol
;
2001 Dec; 19(4): 291-3
Article
in English
| IMSEAR
| ID: sea-36876
ABSTRACT
Serological evidence for Toxoplasma gondii infection in Thai pregnant women was investigated. One thousand six hundred and sixty-nine blood specimens were collected from 838 HIV-seropositive and 831 HIV-seronegative pregnant women attending the antenatal-care clinic at Siriraj Hospital, Bangkok, Thailand, during a two-year period. Toxoplasma IgG antibody was detected, using a solid-phase enzyme-linked immunosorbent assay in which the membrane protein p-30 was the predominant antigen. IgG positive sera were subsequently examined for IgM antibody by the capture antibody enzyme immunoassay. The IgG antibody was found in 450 (53.7%) HIV seropositive women and 44 (5.3%) non-HIV infected women, with a statistically significant difference (p < 0.0001). Three of the 450 HIV-seropositive and 2 of the 44 HIV-seronegative sera with IgG antibody were positive for IgM antibody against T. gondii. This result suggested that HIV seropositive pregnant women had a higher risk of Toxoplasma infection with increase exposure to their offspring.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Toxoplasma
/
Female
/
Humans
/
Pregnancy
/
Antibodies, Protozoan
/
HIV Infections
/
Toxoplasmosis
/
Pregnancy Complications, Parasitic
/
AIDS-Related Opportunistic Infections
Country/Region as subject:
Asia
Language:
English
Journal:
Asian Pac J Allergy Immunol
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS