Neuropsychiatric manifestations in Thai patients with systemic lupus erythematosus.
Asian Pac J Allergy Immunol
;
2002 Sep; 20(3): 179-85
Article
in English
| IMSEAR
| ID: sea-36877
ABSTRACT
Neuropsychiatric (NP) manifestations in patients with systemic lupus erythematosus (SLE) [NPSLE] and prognostic factors were studied in 91 patients. There were 98 NP episodes, of which 78 (79.6%) occurred within the first year of the disease. Twenty-six patients (6.7%) had NPSLE as an initial presentation of the disease. There were seizures in 53 episodes (54.1%), psychosis in 13 (13.3%), acute confusion state in 11 (11.2%), abnormal consciousness in 6 (6.1%), transverse myelitis in 6 (6.1%), peripheral neuropathy in 5 (5.1%), cerebral infarction in 2 (2.0%) and aseptic meningitis in 2 (2.0%). Most forms of NPSLE responded well to high dose corticosteroids. Anti-convulsant therapy could be discontinued within a median duration of 3 months after the SLE activity was under control, and without significant recurrence of seizures. The 5-year and 10-year survival rates of patients with NPSLE were 75.9% and 50.6%, respectively. Patients with NPSLE had significantly more cutaneous vasculitis and less arthritis than those without.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Patient Admission
/
Prognosis
/
Seizures
/
Thailand
/
Female
/
Humans
/
Male
/
Magnetic Resonance Imaging
/
Tomography, X-Ray
/
Cerebrospinal Fluid
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Asian Pac J Allergy Immunol
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS