Ketotifen inhibits allergen-specific T lymphocytes' responses by suppressing antigen presentation with concomitant decrease of HLA-DQ antigen on macrophages.

Kawano, Y; Yoshizawa, I; Baba, M; Noma, T

Kawano, Y; Yoshizawa, I; Baba, M; Noma, T.

Asian Pac J Allergy Immunol ; 1996 Dec; 14(2): 69-79

Article in En | IMSEAR | ID: sea-36949

Subject(s)

Adolescent; Adult; Anti-Allergic Agents/pharmacology; Antigen Presentation/drug effects; Asthma/immunology; Cell Adhesion/drug effects; Cells, Cultured; Child; Child, Preschool; Dose-Response Relationship, Drug; Flow Cytometry; HLA-DQ Antigens/metabolism; Humans; Interferon-gamma/metabolism; Interleukin-2/metabolism; Interleukin-4/metabolism; Ketotifen/pharmacology; Macrophages/drug effects; T-Lymphocytes/drug effects

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Full text: 1 Index: IMSEAR Main subject: Asthma / Humans / T-Lymphocytes / HLA-DQ Antigens / Cell Adhesion / Cells, Cultured / Child / Child, Preschool / Adolescent / Interleukin-4 Language: En Journal: Asian Pac J Allergy Immunol Year: 1996 Type: Article

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