The relevance of specific serum IgG, IgG4 and IgE in the determination of shrimp and crab allergies in Malaysian allergic rhinitis patients.
Asian Pac J Allergy Immunol
;
2001 Mar; 19(1): 7-10
Article
in English
| IMSEAR
| ID: sea-37049
ABSTRACT
The significance of food specific serum IgG4 antibody in food allergy is unclear and this led us to investigate the relevance of specific IgG4, along with IgG and IgE antibodies to two common food allergens in Malaysia. Enzyme-linked immunosorbent assay (ELISA) was used to measure the serum antibodies in 143 allergic rhinitis patients' sera, of which 47 were from patients with clinical indication of shrimp allergy, 46 with clinical indication of crab allergy and 50 without indication to either allergy. Clinical indication of allergy was based on answers to a questionnaire or results of the skin prick test. We found that the elevation of specific IgE or IgG4 is associated with shrimp and crab allergies but elevation of specific IgG is not associated with either allergy. However, the clinical utility of elevated specific IgG and IgG4 levels is pending further investigation.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Shellfish
/
Decapoda
/
Humans
/
Immunoglobulin E
/
Immunoglobulin G
/
Child
/
Child, Preschool
/
Rhinitis, Allergic, Perennial
/
Adolescent
/
Adult
Country/Region as subject:
Asia
Language:
English
Journal:
Asian Pac J Allergy Immunol
Year:
2001
Type:
Article
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