Intranasal budesonide for the treatment of perennial rhinitis in Thai patients.
Asian Pac J Allergy Immunol
;
1988 Dec; 6(2): 116-20
Article
in English
| IMSEAR
| ID: sea-37175
ABSTRACT
The efficacy and tolerability of a new intranasal glucocorticosteroid, budesonide, was evaluated in 28 Thai adult patients with perennial rhinitis. After one week pre-treatment observation period, the nasal spray was given as two puffs into each nostril twice daily (400 micrograms/day) for four weeks. The severity of all nasal symptoms decreased significantly after 1 week treatment reaching a minimal level after 2 weeks. The amounts of antihistamine tablets taken by the patients were also significantly reduced during the treatment with budesonide. Three patients reported adverse effects which were mild and easily tolerated. Morning plasma cortisol levels measured before and after four-week treatment in 15 patients revealed no significant changes. This study suggests that intranasal budesonide is an effective and well-tolerated treatment for perennial rhinitis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pregnenediones
/
Thailand
/
Female
/
Humans
/
Male
/
Administration, Intranasal
/
Hydrocortisone
/
Rhinitis, Allergic, Perennial
/
Medical Records
/
Follow-Up Studies
Type of study:
Observational study
/
Prognostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Asian Pac J Allergy Immunol
Year:
1988
Type:
Article
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