Control of acute myeloid leukemia morbidity in northwest Iran.
Article
in English
| IMSEAR
| ID: sea-37357
ABSTRACT
BACKGROUND:
To investigate protocols of remission induction therapy for prevention of morbidity of acute myeloid leukemia. MATERIALS ANDMETHODS:
The responses of 150 patients to "2+5" and "3+7" protocols during 1996-2003 were assessed and analyzed with the Chi-Square method.RESULTS:
Complete remission was observed in 30% of cases treated with 2 days of daunorubicin and 5 days of cytarabine (2+5 regimen). Remission was increased to 52.5% when patients were treated with 3+7 regimens with the same drugs. Partial remission resulted in 25 and 10 percent of cases, respectively.CONCLUSION:
As in previous studies the 3+7 regimen was demonstrated to be more effective than the 2+5 regimen in our hospital (p=0.0009).
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Remission Induction
/
Humans
/
Drug Administration Schedule
/
Leukemia, Myeloid, Acute
/
Daunorubicin
/
Retrospective Studies
/
Adolescent
/
Adult
/
Cytarabine
/
Iran
Type of study:
Practice guideline
/
Observational study
Country/Region as subject:
Asia
Language:
English
Year:
2005
Type:
Article
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