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Prevalence of high grade squamous intraepithelial lesion (HSIL) and invasive cervical cancer in patients with low grade squamous intraepithelial lesion (LSIL) at cervical pap smear.
Article in English | IMSEAR | ID: sea-37467
ABSTRACT

OBJECTIVE:

To assess the prevalence and factors associated with a histologic diagnosis of high grade squamous intraepithelial lesion (HSIL) and invasive cervical cancer in patients with low grade squamous intraepithelial lesion (LSIL) cervical pap smear findings.

METHODS:

Medical records (including cytology reports, colposcopic impression, and pathologic results from cervical biopsy, endocervical curetting, cervical conization or hysterectomy) of 226 women with LSIL from conventional cervical pap smears during January 2001 to December 2005, who subsequently underwent colposcopic evaluation at our institution, were reviewed.

RESULTS:

Mean age of the patients was 39.0 years. The incidences of LSIL, HSIL, microinvasive cervical cancer were 58.8%, 15.0%, 1.3% respectively. No associations were found between age, parity, contraception, anti-HIV or menstrual status and the detection of HSIL/invasive cervical cancer.

CONCLUSION:

Approximately 16.3 % of LSIL pap smear cases turn out to be HSIL or invasive cervical cancer from histologic diagnosis.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Prognosis / Vaginal Smears / Female / Humans / Carcinoma, Squamous Cell / Uterine Cervical Dysplasia / Uterine Cervical Neoplasms / Prevalence / Risk Factors / Colposcopy Type of study: Diagnostic study / Etiology study / Prevalence study / Prognostic study / Risk factors Language: English Year: 2008 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Prognosis / Vaginal Smears / Female / Humans / Carcinoma, Squamous Cell / Uterine Cervical Dysplasia / Uterine Cervical Neoplasms / Prevalence / Risk Factors / Colposcopy Type of study: Diagnostic study / Etiology study / Prevalence study / Prognostic study / Risk factors Language: English Year: 2008 Type: Article