The prevalence of Chlamydia pneumoniae antibodies in Thai patients with coronary artery disease.
Article
in English
| IMSEAR
| ID: sea-38397
ABSTRACT
Blood samples were obtained from 243 consecutive coronary artery disease (CAD) patients (177 male, 66 female) aged 35-78 years (mean, 61 years) admitted for coronary angiography because of suspected coronary heart disease, and from 115 blood donors (91 male, 24 female) aged 25-60 years (mean, 47 years). Of the 243 CAD patients, 179 (74%) were positive by an ELISA method for Chlamydia pneumoniae antibodies IgG and 132 (54%) were positive for C. pneumoniae IgA. Among the 115 blood donors, 80 (70%) were positive for C. pneumoniae IgG and 49 (43%) were positive for C. pneumoniae IgA. When IgG antibodies were considered, there was no significant difference between CAD patients and healthy controls (OR = 1.29, 95% CI = 0.79-2.10, p > 0.05). In cases of positive IgA antibodies alone, there was a significant difference between CAD patients and healthy controls (OR = 1.58, 95% CI = 1.01-2.4, p = 0.029). If both IgG and IgA antibodies were positive, OR was increased from 1.58 to 1.80 (95% CI = 0.97-3.36, p = 0.044). In conclusion, C. pneumoniae infection is common in Thai people but chronic C. pneumoniae infection is more common in CAD patients than in middle-aged blood donors.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Thailand
/
Aged, 80 and over
/
Aged
/
Female
/
Humans
/
Male
/
Immunoglobulin A
/
Immunoglobulin G
/
Enzyme-Linked Immunosorbent Assay
/
Chlamydia Infections
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Aged80
Country/Region as subject:
Asia
Language:
English
Year:
1999
Type:
Article
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