Mammographic change in hysterectomized women on 0.625 mg/day of conjugated equine estrogen.
Article
in English
| IMSEAR
| ID: sea-38434
ABSTRACT
OBJECTIVE:
To compare the mammographic change before and after conjugated equine estrogen (CEE) 0.625 mg/day in hysterectomized women.DESIGN:
A retrospective descriptive study.SETTING:
Menopause clinic, Maharaj Nakorn Chiang Mai Hospital. MATERIAL ANDMETHOD:
Dedicated mammograms and demographic data of 66 women who had been hysterectomized were reviewed. Post surgical menopausal women were recruited for the study. CEE 0.625 mg/day was given just after the operation. The baseline mammography was done before the initiation of HRT and they were compared with the follow-up mammography performed 12-18 months after therapy. The degree of increase in mammographic density was classified as follows minimal changes (10-25% increased density), moderated change (26-50% increased density), and marked change (> 50% increased density).RESULTS:
The mean age +/- SD was 47 +/- 4.3 years old. The mean duration +/- SD of hormone used was 13.5 +/- 2.4 months. The most common indication for operation was myoma uteri (43.9%). On the baseline mammogram, 5 cases had cystic change and one case had a small circumscribed solid mass suspected to be fibroadenoma. On the follow-up mammograms, there were 2 cases (3.0%) detected to have significantly increased breast density. One was moderately increased and the other was markedly increased, but cystic changes and one fibroadenoma were not changed.CONCLUSION:
CEE has little effect on increased mammographic density.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Postoperative Care
/
Breast
/
Preoperative Care
/
Female
/
Humans
/
Mammography
/
Estrogen Replacement Therapy
/
Retrospective Studies
/
Risk Factors
/
Sampling Studies
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Risk factors
Language:
English
Year:
2004
Type:
Article
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