CD4 + T counts with a course of antituberculous therapy in healthy and HIV-infected patients.

ABSTRACT

A prospective study of CD4 + T lymphocytes with a course of treatment on 20 HIV-infected patients with active tuberculosis receiving antituberculous drugs was compared with 30 non HIV-infected patients with active tuberculosis. The CD4 + T cell counts among non HIV-infected patients were 510 +/- 409 and increased to 634 +/- 382 and 867 +/- 248 at the third and sixth month of therapy. Among HIV-infected patients, the CD4 + T cell counts were 64 +/- 42 and decreased to 40 +/- 23 and 35 +/- 16 in the third and sixth month of therapy (p < 0.05).