Update in pathophysiology and histopathology of focal segmental glomerulosclerosis.
Article
in English
| IMSEAR
| ID: sea-40091
ABSTRACT
Focal segmental glomerulosclerosis (FSGS) is the leading cause of nephrotic syndrome in an adult worldwide. The prevalence of FSGS is estimated as being 20-30% in adults over the age of 15 years and slightly higher (30-35%) in the elderly (age > 60 years). The diagnosis solely relies on pathologic findings, which sclerosis involves some, but not all glomeruli (focal), and sclerosis affects a portion, but not the entire, glomerular tuft (segmental). The pathogenesis remains inconclusive but podocyte injury has been postulated. Even though steroid is the mainstay treatment, only 20-40% of patients are complete respond.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Aged, 80 and over
/
Aged
/
Humans
/
Glomerulosclerosis, Focal Segmental
/
Adolescent
/
Adult
/
Podocytes
/
Middle Aged
/
Nephrotic Syndrome
Limits:
Aged80
Language:
English
Year:
2006
Type:
Article
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